1.0.0.0 Rec­om­men­da­tions and GRADE

1.1.0.0 Rec­om­men­da­tions

Sr.­no.

Recommendations

SoR

QoE

1

In pa­tients with symp­tom­at­ic mi­cro­scop­ic coli­tis, the AGA re­com­mends treat­ment with bu­des­o­nide over no treat­ment for the in­duc­tion of clin­i­cal re­mis­sion.

Strong

Mo­d

Evidence for Recommendation 1

2

In pa­tients with symp­tom­at­ic mi­cro­scop­ic coli­tis, the AGA re­com­mends treat­ment with bu­des­o­nide over me­sala­mine for the in­duc­tion of clin­i­cal re­mis­sion.

Strong

High

Evidence for Recommendation 2

3

In pa­tients with symp­tom­at­ic mi­cro­scop­ic coli­tis in whom bu­des­o­nide ther­a­py is not fea­si­ble, the AGA sug­gests treat­ment with me­sala­mine over no treat­ment for the in­duc­tion of clin­i­cal re­mis­sion.

Con­d

Mod

Evidence for Recommendation 3

4

In pa­tients with symp­tom­at­ic mi­cro­scop­ic coli­tis in whom bu­des­o­nide ther­a­py is not fea­si­ble, the AGA sug­gests treat­ment with bis­muth sa­lic­y­late over no treat­ment for the in­duc­tion of clin­i­cal re­mis­sion.

Cond

Low

Evidence for Recommendation 4

5

In pa­tients with symp­tom­at­ic mi­cro­scop­ic coli­tis in whom bu­des­o­nide ther­a­py is not fea­si­ble, the AGA sug­gests treat­ment with pred­nis­o­lone (or pred­ni­sone) over no treat­ment for the in­duc­tion of clin­i­cal re­mis­sion.

Cond

V Low

Evidence for Recommendation 5

6

In pa­tients with symp­tom­at­ic mi­cro­scop­ic coli­tis, the AGA sug­gests against com­bi­na­tion ther­a­py with cho­lesty­ra­mi­ne and me­sala­mine over me­sala­mine alone for the in­duc­tion of clin­i­cal re­mis­sion.

Cond

Low

Evidence for Recommendation 6

7

In patients with symptomatic microscopic colitis, the AGA suggests against treatment with Boswellia serrata over no treatment for the induction of clinical remission.

Cond

Low

Evidence for Recommendation 7

8

In pa­tients with symp­tom­at­ic mi­cro­scop­ic coli­tis, the AGA sug­gests against treat­ment with pro­bi­ot­ics over no treat­ment for the in­duc­tion of clin­i­cal re­mis­sion.

Cond

Low

Evidence for Recommendation 8

9

For pa­tients with re­cur­rence of symp­toms fol­low­ing dis­con­tin­u­a­tion of in­duc­tion ther­a­py for mi­cro­scop­ic coli­tis, the AGA re­com­mends bu­des­o­nide for main­te­nance of clin­i­cal re­mis­sion.

Strong

Mod

Evidence for Recommendation 9

SoR: Strength of Recommendation
QoE: Quality of Evidence
Strong: Strong Recommendation
Cond: Conditional Recommendation
High: High-Quality Evidence
Mod: Moderate-Quality Evidence
Low: Low-Quality Evidence
V Low: Very Low-Quality Evidence