1.0.0.0 Rec­om­men­da­tions and GRADE

1.1.0.0 Rec­om­men­da­tions

Sr.­no.

Recommendations

SoR

QoE

Anatom­ic lo­ca­tion: Esoph­a­gus

1

In pa­tients un­der­go­ing EGD for dys­pep­sia as the sole in­di­ca­tion, the AGA rec­om­mends against ob­tain­ing rou­tine biop­sies of the nor­mal-ap­pear­ing esoph­a­gus or GE junc­tion re­gard­less of im­mune sta­tus

Strong

V Low

Evidence for Recommendation 1

Anatom­ic lo­ca­tion: Stom­ach

2

In im­muno­com­pe­tent pa­tients un­der­go­ing EGD for dys­pep­sia as the sole in­di­ca­tion, the AGA rec­om­mends ob­tain­ing rou­tine biop­sies of the nor­mal-ap­pear­ing gas­tric body and antrum for the de­tec­tion of HP in­fec­tion if the HP in­fec­tion sta­tus is un­known.

Strong

Mod
Evidence for Recommendation 2

3

In im­muno­com­pro­mised pa­tients un­der­go­ing EGD for dys­pep­sia as the sole in­di­ca­tion, the AGA rec­om­mends ob­tain­ing rou­tine biop­sies of the nor­mal-ap­pear­ing gas­tric body and antrum for the de­tec­tion of HP in­fec­tion if the HP in­fec­tion sta­tus is un­known.

Strong

V Low
Evidence for Recommendation 3

4

When ob­tain­ing biop­sies from the nor­mal-ap­pear­ing gas­tric body and antrum for the de­tec­tion of HP in­fec­tion, the AGA sug­gests fol­low­ing the 5-biop­sy Syd­ney Sys­tem with all spec­i­mens placed in the same jar.

Cond

Mod
Evidence for Recommendation 4

5

When biop­sies are ob­tained from the nor­mal-ap­pear­ing gas­tric body and antrum for the de­tec­tion of HP in­fec­tion, the AGA sug­gests not ob­tain­ing au­to­mat­ic spe­cial stain­ing of the spec­i­mens.

Cond

Mod
Evidence for Recommendation 5

Anatom­ic lo­ca­tion: Duo­de­num

6

In pa­tients un­der­go­ing EGD for dys­pep­sia as the sole in­di­ca­tion, and in the ab­sence of signs or symp­toms as­so­ci­at­ed with an in­creased risk of celi­ac dis­ease, the AGA sug­gests not ob­tain­ing rou­tine biop­sies of the nor­mal-ap­pear­ing duo­de­num to de­tect celi­ac dis­ease.

Cond

V Low
Evidence for Recommendation 6

7

In im­muno­com­pro­mised pa­tients un­der­go­ing EGD for dys­pep­sia as the sole in­di­ca­tion, the AGA sug­gests ob­tain­ing rou­tine biop­sies of the nor­mal-ap­pear­ing duo­de­num for the de­tec­tion of GVHD in post−al­lo­gene­ic tis­sue trans­plan­ta­tion pa­tients and for op­por­tunis­tic in­fec­tions.

Cond

V Low
Evidence for Recommendation 7

8

When biop­sies are ob­tained from the nor­mal-ap­pear­ing duo­de­num, the AGA sug­gests not per­form­ing rou­tine spe­cial stain­ing of the spec­i­mens.

Cond

V Low
Evidence for Recommendation 8

SoR: Strength of Recommendation
QoE: Quality of Evidence
Strong: Strong Recommendation
Cond: Conditional Recommendation
High: High-Quality Evidence
Mod: Moderate-Quality Evidence
Low: Low-Quality Evidence
V Low: Very Low-Quality Evidence